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Quantitative assessment of dielectric parameters for membrane lipid bi-layers from rf permittivity measurements

TitoloQuantitative assessment of dielectric parameters for membrane lipid bi-layers from rf permittivity measurements
Tipo di pubblicazioneArticolo su Rivista peer-reviewed
Anno di Pubblicazione2009
AutoriMerla, Caterina, Liberti M., Apollonio F., and d'Inzeo G.
RivistaBioelectromagnetics
Volume30
Paginazione286-298
ISSN01978462
Parole chiavearticle, Biological, biological model, cell membrane, dielectric constant, Electric conductivity, electric field, electric model, experimental study, lipid bilayer, Lipid Bilayers, liposome, membrane permeability, microdosimetry, Models, priority journal, quantitative analysis, Radio Waves, radiofrequency radiation, radiometry, Temperature, Theoretical, theoretical model, theoretical study, Unilamellar Liposomes
Abstract

{In this article, we propose and validate theoretical and experimental methods to quantitatively assess the Debye dielectric model of membrane lipid bi-layers. This consists of two steps: permittivity measurements of biological solutions (liposomes), and estimation of the model parameters by inverse application of the Effective Medium Theory. The measurements are conducted in the frequency domain between 100 MHz and 2 GHz using a modified coaxial connector, at the temperatures of 27 and 30 °C. Estimations have been performed using a three-layered model based on the Maxwell-Wagner formulation. Debye parameters (mean value ± standard error) found from fitting experimental data are: εs- 11.69 ±0.09, ε∞ = 4.00 ±0.07

Note

cited By 34

URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-66149142275&doi=10.1002%2fbem.20476&partnerID=40&md5=e9bb8e0f030dc3278dc5330adac81e00
DOI10.1002/bem.20476
Citation KeyMerla2009286