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Electropermeabilization of isolated cancer stem cells with a novel and versatile nanosecond pulse generator

TitoloElectropermeabilization of isolated cancer stem cells with a novel and versatile nanosecond pulse generator
Tipo di pubblicazionePresentazione a Congresso
Anno di Pubblicazione2018
AutoriDavies, I.W., Merla Caterina, Casciati Arianna, Zambotti Alessandro, Bishop J., Hodgkins G., Palego C., and Hancock C.P.
Conference NameIMBioc 2018 - 2018 IEEE/MTT-S International Microwave Biomedical Conference
Parole chiaveCancer stem cells, cytology, Diseases, Electric fields, Electro-manipulation, electroporation, High voltage, molecular biology, Nanosecond pulse, Pulse generators, pulsed electric field, Stem cells
Abstract

This paper presents the use of a novel electro-poration generator with an artificial 50Ω buffer for possible real-time neutralization of cancer stem cells. The results from an initial bench study investigates the development of an electro-poration generator capable of delivering non-thermal treatment with an original cuvette housing unit and its effects on isolated cancer stem cell. Initial permeabilization investigation of cancer stem cells were conducted, indicating that the developed protocols and devices have a strong potential future use in achieving electro-manipulation of cancer stem cells. © 2018 IEEE.

URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85052373906&doi=10.1109%2fIMBIOC.2018.8428941&partnerID=40&md5=b64a9a99e28c2a84471f736573cbd214
DOI10.1109/IMBIOC.2018.8428941
Citation KeyDavies2018106