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A review on microbial products and their perspective application as antimicrobial agents

TitleA review on microbial products and their perspective application as antimicrobial agents
Publication TypeArticolo su Rivista peer-reviewed
Year of Publication2021
AuthorsRani, A., Saini K.C., Bast F., Varjani S., Mehariya S., Bhatia S.K., Sharma N., and Funk C.
Keywords4 dihydroxy phenyl) 2 formamidoacrylate, Acinetobacter baumannii, Actinobacteria, Alternaria, amphotericin B, antibacterial activity, antibiotic agent, antibiotic resistance, Antifungal activity, antifungal resistance, antimicrobial activity, arisugacin K, asperamide, aspergicin, Aspergillus flavus, Aspergillus niger, asperitaconic acid A, asperitaconic acid B, asperitaconic acid C, asperterrein, Bacillus amyloliquefaciens, Bacillus cereus, Bacillus licheniformis, Basidiomycetes, Bifidobacterium bifidum, botrybel, botryorhodine I, botryorhodine J, Candida albicans, ceftazidime, Cephalosporium, chermesin A, chermesin B, Chlamydomonas reinhardtii, Chloramphenicol, chrisin, clarithromycin, clavatol, comazaphilone C, comazaphilone D, comazaphilone E, Cytotoxicity, daptomycin, delvo nis, delvocid, Energy dispersive X ray spectroscopy, Enterococcus faecalis, ergosterdiacid A, ergosterdiacid B, erythromycin, Escherichia coli, ethyl (z) 3 (3, flavuside A, flavuside B, fluconazole, food preservative, Food processing, Fusarium graminearum, Fusarium verticillioides, halocin, Helicobacter pylori, high performance thin layer chromatography, IC50, infrared spectroscopy, isorhodop tilometrin 1 methyl ether, jesterone, Klebsiella pneumoniae, kodiak, Lactobacillus paracasei, lactone derivative, lanthionine, lipopeptide, Magnaporthe oryzae, methicillin resistant Staphylococcus aureus, methicillin susceptible Staphylococcus aureus, Micrococcus luteus, Micromonospora, minimum inhibitory concentration, natamycin, nisin, Nocardia, nonhuman, novasin, Nuclear magnetic resonance spectroscopy, ochramide B, peniciadametizine A, penicibilaene A, Penicillium chrysogenum, penicisteroid A, Photobacterium, Pichia kudriavzevii, prebiotic agent, probiotic agent, Pseudomonas aeruginosa, review, Rhizoctonia solani, rhizovital, schevalone E, Sclerotinia sclerotiorum, serenade, silver nanoparticle, speradine A, spiculisporic acid F, spiculisporic acid G, spironolactone, Staphylococcus epidermidis, taegro, terretonin G, trichoderin A, Trichophyton mentagrophytes, unclassified drug, vancomycin, versiperol A, Vibrio harveyi, Vibrio parahaemolyticus, xylarinonericin, xylarinonericin D, ylarinonericin E

Microorganisms including actinomycetes, archaea, bacteria, fungi, yeast, and microalgae are an auspicious source of vital bioactive compounds. In this review, the existing research regard-ing antimicrobial molecules from microorganisms is summarized. The potential antimicrobial compounds from actinomycetes, particularly Streptomyces spp.; archaea; fungi including endophytic, filamentous, and marine-derived fungi, mushroom; and microalgae are briefly described. Further-more, this review briefly summarizes bacteriocins, halocins, sulfolobicin, etc., that target multiple-drug resistant pathogens and considers next-generation antibiotics. This review highlights the pos-sibility of using microorganisms as an antimicrobial resource for biotechnological, nutraceutical, and pharmaceutical applications. However, more investigations are required to isolate, separate, purify, and characterize these bioactive compounds and transfer these primary drugs into clinically approved antibiotics. © 2021 by the authors. Li-censee MDPI, Basel, Switzerland.


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Citation KeyRani2021