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High-Frequency Dielectrophoresis Characterization of Differentiated vs Undifferentiated Medulloblastoma Cells

TitleHigh-Frequency Dielectrophoresis Characterization of Differentiated vs Undifferentiated Medulloblastoma Cells
Publication TypePresentazione a Congresso
Year of Publication2018
AuthorsManczak, R., Saada S., Tanori Mirella, Casciati A., Dalmay C., Bessette B., Begaud G., Battu S., Blondy P., Jauberteau M.O., Kaynak C.B., Kaynak M., Palego C., Merla Caterina, Tanno Barbara, Mancuso Mariateresa, Lalloue F., and Pothier A.
Conference NameEMF-Med 2018 - 1st EMF-Med World Conference on Biomedical Applications of Electromagnetic Fields and COST EMF-MED Final Event with 6th MCM
Keywordscell culture, Cell lines, Cell phenotype, Cells, Cross-over frequencies, Dielectric properties, Dielectric spectroscopy, Electromagnetic Fields, Electrophoresis, Frequency dependent, High frequency HF, Individual cells, Medical applications, medulloblastoma, Undifferentiated cells
Abstract

This paper introduces first results of characterization of medullobastoma cell lines using high frequency dielectrophoresis (HF-DEP) approach at frequencies ranging up to few hundreds of MHz. Such technique enables accessing intracellular dielectric property specificities on individual cells. Actually, the frequency dependent DEP behavior of several medullobastoma cells has been studied showing clear differences between cells from different types which correlate well the biological specificity established though cell phenotype characterization. These results should pave the way to novel and complementary cell discrimination approach based on a label free HF-DEP crossover frequency signature measurement. © 2018 FESB, University of Split.

URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85057718062&doi=10.23919%2fEMF-MED.2018.8526006&partnerID=40&md5=aefb0ece2faae4a076959a687550c090
DOI10.23919/EMF-MED.2018.8526006
Citation KeyManczak2018