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Progetto InnCoCells

Innovative high-value cosmetic products from plants and plant cells

logo progetto InnCoCells
Tipo di Finanziamento: 
Programmi dell'Unione Europea
Programma UE: 
da 1 Maggio 2021 a 30 Aprile 2025
Ruolo ENEA: 
Responsabile di Progetto: 
Gianfranco Diretto
Alessia FioreSarah FruscianteOlivia DemurtasSilvia MassaLuca NardiOmbretta Presenti
In corso

In the most recent economic forecast, the global cosmetics market is predicted to reach $438.4 billion by 2026 with a compound annual growth rate (CAGR) of 5.1%. The market is segmented by categories such as hair care, skin care, makeup, deodorants/toiletries, edible cosmetics and perfumes, with skin care accounting for ~39%, haircare for ~21% and makeup for ~19%.

Cosmetic ingredients may work as fragrances, colorants, moisturisers, thickening agents and stabilisers, but the most valuable functions include sun protection, anti-ageing, anti-wrinkle, whiteners and antimicrobials. In this context, the InnCoCells project aims to develop innovative and sustainable plant-based production processes for the commercial exploitation of scientifically validated cosmetic ingredients based on underutilised plant resources.

Within the different industrial segments, InnCoCells project will focus especially on ingredients and products for the skin care, which is consistently the most profitable.

The production process pipeline of the selected plant resources will be optimized for being profitable and sustainable using cell cultures, aeroponics and greenhouse/field cultivation. In addition, InnCoCells will apply systematic approaches including metabolic engineering tools to optimise growth conditions and the yields of valuable bioactive, small-molecule compounds and ingredients. The optimised processes will be demonstrated by pilot-scale production and subsequent product extraction/purification.

The ingredients and extracts will be evaluated using a unique panel of innovative enzyme based and cell-based assays to ensure safety and validate claimed activities based on robust scientific data without animal testing.

As final objective, InnCoCells will bring at least ten cosmetic ingredients to the pre-commercial stage and includes a cascade biorefinery concept in which by-products and biowaste are utilised for the extraction of further bioactive molecules. Along the different steps, the processes will be characterised by techno-economic assessment and life cycle analysis to ensure economic feasibility and a reduced environmental footprint. Overall, the InnCoCells consortium includes eight SMEs and one large company from the cosmetic sector among the 17 partners to facilitate exploitation.