| Title | Broadband electrical detection of individual biological cells |
|---|---|
| Publication Type | Articolo su Rivista peer-reviewed |
| Year of Publication | 2014 |
| Authors | Ning, Y., Multari C., Luo X., Palego C., Cheng X., Hwang J.C.M., Denzi A., Merla Caterina, Apollonio F., and Liberti M. |
| Journal | IEEE Transactions on Microwave Theory and Techniques |
| Volume | 62 |
| Pagination | 1905-1911 |
| Keywords | Biological cells, Biological engineering, Biological liquids, Biomedical transducers, Biosensors, Electrodes, Electrophoresis, Microstripes, Microwave measurement, Sensitivity |
| Abstract | To resolve the dilemma of cell clogging or solution parasitics encountered by Coulter counters and to evolve a general-purpose electrical detection technique, we used broadband microwave measurements to overcome electrode polarization, ac dielectrophoresis to precisely place cells between narrowly spaced electrodes, and relatively wide microfluidic channels to prevent cell clogging. This unique combination of approaches resulted in reproducible sensing of single Jurkat and HEK cells, both live and dead, of different cultures at different times. © 2014 IEEE. |
| Notes | cited By 26 |
| URL | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84930384810&doi=10.1109%2fTMTT.2014.2342660&partnerID=40&md5=a10f61927b71eee4c50ac994fd479880 |
| DOI | 10.1109/TMTT.2014.2342660 |
| Citation Key | Ning20141905 |
