Genome sequence and analysis of the tuber crop potato.

TitleGenome sequence and analysis of the tuber crop potato.
Publication TypeArticolo su Rivista peer-reviewed
Year of Publication2011
AuthorsXu, Xun, Pan Shengkai, Cheng Shifeng, Zhang Bo, Mu Desheng, Ni Peixiang, Zhang Gengyun, Yang Shuang, Li Ruiqiang, Wang Jun, Orjeda Gisella, Guzman Frank, Torres Michael, Lozano Roberto, Ponce Olga, Martinez Diana, De la Cruz Germán, Chakrabarti S K., Patil Virupaksh U., Skryabin Konstantin G., Kuznetsov Boris B., Ravin Nikolai V., Kolganova Tatjana V., Beletsky Alexey V., Mardanov Andrei V., Di Genova Alex, Bolser Daniel M., Martin David M. A., Li Guangcun, Yang Yu, Kuang Hanhui, Hu Qun, Xiong Xingyao, Bishop Gerard J., Sagredo Boris, Mejía Nilo, Zagorski Wlodzimierz, Gromadka Robert, Gawor Jan, Szczesny Pawel, Huang Sanwen, Zhang Zhonghua, Liang Chunbo, He Jun, Li Ying, He Ying, Xu Jianfei, Zhang Youjun, Xie Binyan, Du Yongchen, Qu Dongyu, Bonierbale Merideth, Ghislain Marc, Herrera Maria Del Rosari, Giuliano Giovanni, Pietrella Marco, Perrotta Gaetano, Facella Paolo, O’Brien Kimberly, Feingold Sergio E., Barreiro Leandro E., Massa Gabriela A., Diambra Luis, Whitty Brett R., Vaillancourt Brieanne, Lin Haining, Massa Alicia N., Geoffroy Michael, Lundback Steven, Dellapenna Dean, C Buell Robin, Sharma Sanjeev Kumar, Marshall David F., Waugh Robbie, Bryan Glenn J., Destefanis Marialaura, Nagy Istvan, Milbourne Dan, Thomson Susan J., Fiers Mark, Jacobs Jeanne M. E., Nielsen Kåre L., Sønderkær Mads, Iovene Marina, Torres Giovana A., Jiang Jiming, Veilleux Richard E., Bachem Christian W. B., de Boer Jan, Borm Theo, Kloosterman Bjorn, van Eck Herman, Datema Erwin, Hekkert Bas Te Lintel, Goverse Aska, van Ham Roeland C. H. J., and Visser Richard G. F.
JournalNature
Volume475
Pagination189-195
Date Published2011
ISSN1476-4687
Keywordsangiosperm, article, asterids, Breeding, cladistics, depression, Disease resistance, Evolution, evolutionary biology, Food security, Gene duplication, Gene expression, gene expression regulation, gene mutation, gene sequence, Genes, genetic analysis, Genetic Variation, Genome, Genomics, Grain, haplotype, Haplotypes, heterozygosity, heterozygote, homozygosity, Homozygote, Immunity, Inbreeding, inbreeding depression, Innate, Magnoliophyta, Molecular, Molecular Sequence Annotation, Molecular Sequence Data, Multigene Family, nonhuman, Plant, Plant Diseases, Ploidies, potato, priority journal, Sequence Analysis, Solanum tuberosum, tuber
Abstract

Potato (Solanum tuberosum L.) is the world’s most important non-grain food crop and is central to global food security. It is clonally propagated, highly heterozygous, autotetraploid, and suffers acute inbreeding depression. Here we use a homozygous doubled-monoploid potato clone to sequence and assemble 86% of the 844-megabase genome. We predict 39,031 protein-coding genes and present evidence for at least two genome duplication events indicative of a palaeopolyploid origin. As the first genome sequence of an asterid, the potato genome reveals 2,642 genes specific to this large angiosperm clade. We also sequenced a heterozygous diploid clone and show that gene presence/absence variants and other potentially deleterious mutations occur frequently and are a likely cause of inbreeding depression. Gene family expansion, tissue-specific expression and recruitment of genes to new pathways contributed to the evolution of tuber development. The potato genome sequence provides a platform for genetic improvement of this vital crop.

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URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-79960422847&doi=10.1038%2fnature10158&partnerID=40&md5=4c082b83fb1a157efc4c6a4983c5c491
DOI10.1038/nature10158