| Title | CD8+ T cells: GITR matters |
|---|---|
| Publication Type | Articolo su Rivista peer-reviewed |
| Year of Publication | 2012 |
| Authors | Ronchetti, Simona, Nocentini Giuseppe, Petrillo Maria Grazia, and Riccardi Carlo |
| Journal | The Scientific World Journal |
| Volume | 2012 |
| Type of Article | Review |
| ISSN | 1537744X |
| Keywords | CD4+ T lymphocyte, CD8+ T lymphocyte, cell function, cytokine production, gamma interferon, gene, Gene expression, gene function, glucocorticoid induced tumor necrosis factor receptor related gene, human, Neoplasm, nonhuman, review, tumor immunity, virus immunity, virus infection |
| Abstract | As many members of the tumor necrosis factor receptor superfamily, glucocorticoid-induced TNFR-related gene (GITR) plays multiple roles mostly in the cells of immune system. CD8+ T cells are key players in the immunity against viruses and tumors, and GITR has been demonstrated to be an essential molecule for these cells to mount an immune response. The aim of this paper is to focus on GITR function in CD8+ cells, paying particular attention to numerous and recent studies that suggest its crucial role in mouse disease models. © 2012 Simona Ronchetti et al. |
| Notes | Cited by: 24; All Open Access, Gold Open Access, Green Open Access |
| URL | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84861022622&doi=10.1100%2f2012%2f308265&partnerID=40&md5=153f02e09af157974b8462b731d2d2fc |
| DOI | 10.1100/2012/308265 |
| Citation Key | Ronchetti2012 |
| PubMed ID | 22654588 |
