| Title | Antiproliferative activity of lichen extracts on murine myeloma cells |
|---|---|
| Publication Type | Articolo su Rivista peer-reviewed |
| Year of Publication | 2009 |
| Authors | Triggiani, Doriana, Ceccarelli D., Tiezzi A., Pisani T., Munzi S., Gaggi C., and Loppi S. |
| Journal | Biologia |
| Volume | 64 |
| Pagination | 59-62 |
| ISSN | 00063088 |
| Keywords | Evernia prunastri, Mammalia, Murinae, Xanthoria parietina |
| Abstract | In the present study we report some preliminary results concerning the evaluation of antiproliferative activity on murine myeloma cells (P3X63-Ag8.653) of crude extracts of two common lichen species, Evernia prunastri and Xanthoria parietina. The results were evaluated by means of the MTT [3-(4,5- dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] test, which is commonly used to assess the activity of living cells through mitochondrial dehydrogenases. They indicated that extracts of E. prunastri had no effect, while those of X. parietina significantly affected murine myeloma cell proliferation, with a reduction down to 75% for methanolic extracts. This opens perspectives for deeper investigations extended also to other mammalian cell lines. ©2009 Institute of Botany, Slovak Academy of Sciences. |
| Notes | cited By 34 |
| URL | https://www.scopus.com/inward/record.uri?eid=2-s2.0-59149100028&doi=10.2478%2fs11756-009-0005-y&partnerID=40&md5=d72e2791eadafa5a4b9721bca7460ae4 |
| DOI | 10.2478/s11756-009-0005-y |
| Citation Key | Triggiani200959 |
