The coffee genome provides insight into the convergent evolution of caffeine biosynthesis.

TitleThe coffee genome provides insight into the convergent evolution of caffeine biosynthesis.
Publication TypeArticolo su Rivista peer-reviewed
Year of Publication2014
AuthorsDenoeud, France, Carretero-Paulet Lorenzo, Dereeper Alexis, Droc Gaëtan, Guyot Romain, Pietrella Marco, Zheng Chunfang, Alberti Adriana, Anthony François, Aprea Giuseppe, Aury Jean-Marc, Bento Pascal, Bernard Maria, Bocs Stéphanie, Campa Claudine, Cenci Alberto, Combes Marie-Christine, Crouzillat Dominique, Da Silva Corinne, Daddiego Loretta, De Bellis Fabien, Dussert Stéphane, Garsmeur Olivier, Gayraud Thomas, Guignon Valentin, Jahn Katharina, Jamilloux Véronique, Joët Thierry, Labadie Karine, Lan Tianying, Leclercq Julie, Lepelley Maud, Leroy Thierry, Li Lei-Ting, Librado Pablo, Lopez Loredana, Muñoz Adriana, Noel Benjamin, Pallavicini Alberto, Perrotta Gaetano, Poncet Valérie, Pot David, Pot David, Rigoreau Michel, Rouard Mathieu, Rozas Julio, Tranchant-Dubreuil Christine, VanBuren Robert, Zhang Qiong, Andrade Alan C., Argout Xavier, Bertrand Beno\^\it, de Kochko Alexandre, Graziosi Giorgio, Henry Robert J., Henry Robert J., Ming Ray, Nagai Chifumi, Rounsley Steve, Sankoff David, Giuliano Giovanni, Albert Victor A., Wincker Patrick, and Lashermes Philippe
JournalScience (New York, N.Y.)
Volume345
Pagination1181-4
Date Published2014 Sep 5
ISSN1095-9203
KeywordsCaffeine, Coffea, Evolution, Genome, Methyltransferases, Molecular, Phylogeny, Plant, Plant Proteins
Abstract

Coffee is a valuable beverage crop due to its characteristic flavor, aroma, and the stimulating effects of caffeine. We generated a high-quality draft genome of the species Coffea canephora, which displays a conserved chromosomal gene order among asterid angiosperms. Although it shows no sign of the whole-genome triplication identified in Solanaceae species such as tomato, the genome includes several species-specific gene family expansions, among them N-methyltransferases (NMTs) involved in caffeine production, defense-related genes, and alkaloid and flavonoid enzymes involved in secondary compound synthesis. Comparative analyses of caffeine NMTs demonstrate that these genes expanded through sequential tandem duplications independently of genes from cacao and tea, suggesting that caffeine in eudicots is of polyphyletic origin.

Notes

cited By 360

URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84907200661&doi=10.1126%2fscience.1255274&partnerID=40&md5=cf40c6d9733d08ab3860dbbcfd5e1f71
DOI10.1126/science.1255274